Kagocel instructions for use tablets reviews. Antiviral drug Kagocel: effectiveness and dosage. Instructions for use for children

No person is immune from colds. Adults, children, the elderly and athletes can encounter the problem, so you need to know which drugs can quickly have a positive effect, relieve symptoms and act on the source. The drug Kagocel in compact form is an effective medicine used in the main course of therapeutic treatment, as well as for prophylactic use during the period of greatest risk of infection. Group – antiviral and immunomodulatory agents.

The constituent elements of Kagocel indicate its natural origin, the absence of components of chemical origin, and reduce the likelihood of an allergic reaction and side effects. The main component that starts to work is Kagocel. One tablet of this component contains 12 mg. The effectiveness of the work is complemented by substances such as:

  • calcium stearate (salt of calcium and stearic acid);
  • crospovidone (improves the process of substance release, accelerates chemical reactions);
  • a substance called povidone is an enterosorbent in its properties;
  • lactose monohydrate (a component that people intolerant to this substance should pay attention to).

Additionally, the composition includes a natural and completely safe product - starch obtained from potatoes. The drug is packaged in cardboard boxes and blisters. One contains 10 tablets and instructions on how to use the product to achieve maximum results.

The main active ingredient (kagocel) is a unique composition that is aimed at stimulating natural substances. As a result of the synthesis launched by it, the body resumes (strengthens) the production of its own antiviral proteins, as well as interferons. The work is intensive, but does not lead to negative processes. The main component is a preparation of biological synthesis - a combination of cotton polymer and cellulose, resulting in a complex sodium salt. The therapeutic effect in this case is mild, the action is direct and indirect. Since the effect is not intense, the medication can be used to treat colds and viral infections that occur in childhood.

The peculiarities of the drug’s operation are expressed in the fact that after taking the tablets according to the instructions or medical recommendation, immediately after the first use, the amount of interferons produced increases. This process continues over the next two days. Also, the largest amount is found in the intestines - here the level of interferons increases during the first 4 hours after administration.

The maximum possible positive effect from use is observed if the therapeutic effect was started within the first 4 days from the onset of symptoms. Such an impact is directly related to the rapid spread of viruses inside cells, since during this period they are most sensitive and vulnerable to the effects of interferons directed at them. In accordance with the characteristics of interferon, Kagocel has the following medicinal properties:

  • elimination of microbes (any microorganisms cannot resist the effects of the medication for long);
  • antiviral (viruses stop developing, weaken and die without causing serious harm to the body if the product is started in a timely manner);
  • strengthening the natural strength of the immune system;
  • radioprotector.

About 20% of the active substance, after carrying out the necessary therapy to restore strength and function of the immune system, accumulates in the liver, but the drug is excreted through the gastrointestinal tract - up to 91% and the remainder (about 10%) with liquids. The accumulation of the main component and excipients in the body was not observed during medical studies.

Preventive or therapeutic use of the drug Kagocel for colds shows good results - the recovery process proceeds faster, symptoms disappear 1-3 days after the start of treatment. In addition to the usual acute respiratory infections, the medication is included in the active recovery program for adults and children if they are diagnosed with:

  • diseases that have developed in the body due to the activity of viruses (ARVI);
  • influenza (including those accompanied by severe symptoms);
  • herpes (occurring in a simple form).

The product is also a good preventive drug that does not burden the body, but forces all processes responsible for the strength of the immune system to activate.

The drug will help eliminate such manifestations of colds as:

  • weakness (even if it is too strong);
  • general (pronounced) malaise caused by exposure to viruses and infections;
  • muscle pain (often occurs during ARVI or flu);
  • burning sensation with pain in the throat.

The drug has a complex effect, due to which, already on the first day after taking it, a person feels a clear relief of the condition; if the disease is mild, then there is an influx of strength and energy.

The use of a medication may be prohibited if a person has one or more contraindications:

  • individual intolerance to the elements that form the drug;
  • sensitivity to the drug;
  • waiting for the baby to be born (any trimester);
  • natural feeding period;
  • hereditary characteristics;
  • acquired intolerance to the drug or one of the components;
  • age – under 3 years;
  • insufficient production of enzymes (lactase).

Also, the group of patients who have lactose intolerance or a disorder such as glucose-galactose malabsorption will also need to stop taking it.

Attention! In order to avoid deterioration of the condition, you must first apply for a diagnostic test to determine the condition and characteristics of the body.

Using the drug Kagocel for colds

In order to defeat a cold-like disease with maximum efficiency, you need to carefully follow the recommendations for use. Thus, tablets are intended exclusively for oral use. The convenience of treatment is that this process does not depend on food intake - the medication works equally well both before and after meals.

Attention should be paid to age characteristics and the type of disease that needs to be eliminated. For the treatment of adult patients from manifestations of ARVI and influenza, in 95% of cases, 2 tablets are prescribed three times a day (this regimen must be followed for 1-2 days of treatment). Then (on the 3-4th day of therapy) the dosage is reduced, and to obtain positive results you need to use 1 tablet, but also three times a day. The total duration of the course is 4 days, during which you will take 18 small tablets of the medicinal drug (almost 2 packs).

If the medication is prescribed for prophylactic purposes to prevent diseases caused by the negative activity of viruses or influenza (acute respiratory infections with complications), then the course of treatment lasts 7 days. A special feature will be the use of 2 tablets once a day for 1-2 days, then you need to take a break for 5 days and repeat the intake again according to the 1-2 day regimen. If necessary, this method is repeated 1-2 more times.

If a person knows how to take Kagocel medication for a cold, since he often encounters this disease, then he may not have information about how to get rid of herpes. To get rid of the problem with the help of medication, you will need to take 2 tablets 3 times a day for 5 days (you will need to use 30 tablets in total).

Medical research shows that herpes is a common problem among patients of any age group. Official statistics indicate that 90% of people encounter the herpes virus. Medical studies involving 146 people showed that 115 of them had the herpes virus.

Studies of the therapeutic properties were carried out using a standard dose of medication (tablets with 12 mg of active substance). In order to get real results, patients were divided into 3 groups:

  • taking only Kagocel to get rid of herpes;
  • using it with the addition of Acyclovir to therapy;
  • treated exclusively with Acyclovir.

If there was primary herpes or a recurrent disease, then the same treatment was used for patients from the first group - 2 Kagocel tablets 3 times a day, the course of therapy was 5 days. For those who were in the second group, the following therapy was used - 2 tablets of Kagocel 3 times a day and 1 tablet of Acyclovir per day, the duration of the course was also 5 days. Patients in the third group received only Acyclovir as a composition that can cope with most forms of hepatitis - 1 tablet per day. The symptoms of herpes in all groups completely disappeared on the 5th day, but in patients from the second group there was a complete cure already on the 3rd day after the start of therapy. In those who were in the group treated exclusively with Acyclovir, manifestations were observed on the 6th day after the start of the course of treatment. As a result of therapy using Kagocel, in 22% of people the disease does not recur, in 50% of cases there are only 1-2 relapses, in 27% there were no more than 3 repetitions of the condition eliminated during the first treatment.

The maximum effect was recorded during complex treatment - Kagocel and Acyclovir. In this case, 47% had no relapses at all, and the rest suffered no more than 2 recurrences of the disease. During the tests, no side effects were identified, and the symptoms of herpes were milder. Timely use of the drug in combination with the classic Acyclovir for the treatment of herpes allows you to get a better result than treatment using only the second drug.

Features of treatment of children with Kagocel

Children, due to the anatomical and natural characteristics of the body, encounter colds more often than adults or adolescents. The treatment regimen for children differs from that for those over 13 years old. Thus, for children aged 3-6 years, that is, preschoolers and kindergarteners, in order to effectively influence the symptoms and causes of diseases of viral origin and influenza, it is necessary to use 1 small tablet 2 times a day for therapy on days 1-2. On days 3-4 of treatment - 1 tablet once a day. The total duration of the course is 4 days, you will need to use 6 tablets.

For children who are already 6 years old and under 13 years old, for high-quality treatment of colds caused by viruses and influenza, the following therapy is carried out - 1-2 days: 1 tablet 3 times a day, 3-4 days of treatment - 1 tablet 2 times a day. The course of action lasts 4 days, in total you will need to use 10 tablets (1 full pack).

Children over 3 years old can undergo prevention of colds, ARVI and flu. It continues in courses of 7 days (a full week). The peculiarity of such an effect without a load on a fragile child’s body: 1-2 days - 1 tablet per day, then 3-7 days - a break. This is followed by a repetition of such an impact. These dosages should not be exceeded, regardless of age.

To include Kagocel in restorative therapy, it must be taken into account that for children under 3 years of age there is not enough information to guarantee complete safety. Therefore, the prevention of colds and complex manifestations of the effects of viruses (ARVI) should begin according to the recommended option, when the baby is already 3 years old.

Basic treatment begins at 6 years of age. In this case, the medication begins to actively work, triggering processes in the same way as in adults - its own production of interferon is activated and stimulated. That is why this component is necessary for the seasonal strengthening of the immune system; Kagocel promotes sufficient interferon production without negative consequences. It also actively alleviates the symptoms of a cold if it appears or develops by the time treatment begins. There are also no side effects.

Studies were conducted that revealed the effectiveness of the drug in children at the time of the onset of exposure to existing manifestations of colds with clear symptoms. Medical research created 2 groups of patients (6-13 years old), each of the children was sick for 2 days before they began to receive the drug for therapeutic effects:

  • recovery measures in the first group (only Kagocel was used) are carried out according to the following scheme: days 1-2 of treatment include the use of 2 tablets (1 in the morning and 1 in the evening) per day. Then the dosage is increased, and on days 3-4, 2 tablets are used 2 times a day. The total amount of medication in the course is 10 tablets (1 package);
  • restorative measures for those who were included in the second group consisted of the use of a “placebo” - the course of such an effect was also 4 days.

Additionally, in all groups, accompanying procedures were used to eliminate the main causes and symptoms:

  • inhalation;
  • taking cough suppressants (depending on whether it is dry or “wet”);
  • using age-appropriate drops or spray for a runny nose;
  • use of means to relieve allergic manifestations (if necessary).

Drugs such as antivirals or immunostimulants were not used to ensure the purity of the information obtained on the drug.

The results of studies in babies and children who used Kagocel in the recovery program showed that the main symptoms, including fever, disappeared already 1-2 days after the start of use. Data for the second group (where a “placebo” was used in addition to other methods of influencing the manifestations of a cold or acute respiratory viral infection) - the symptoms disappeared only on the 5th day after the start of treatment.

The results of the observation showed that the main symptoms of colds, which include a runny nose, severe inflammation of the mucous membranes of the throat and tonsils in children belonging to the first group, weakened and began to disappear on the first day of treatment. The runny nose completely disappeared within 3-4 days. The second group of children began to recover only on the 5th-6th day. It turns out that for those who use Kagocel as part of the rehabilitation and treatment program, the recovery time is reduced by half - from 7-8 days to 3-4 days.

As a result, the features of treatment in children come down to the following: the manifestation of symptoms (even those caused by exposure to a viral agent) is reduced. And they disappear completely after 3, maximum 4 days. If interferon was not enough to fully counteract the negative effects, taking Kagocel will help launch the natural production of this component without harm or burden on the child’s body. No side effects were identified during or after the study. The drug is also well tolerated by children throughout the entire period of use.

If signs of drug overdose were noted during treatment, then all negative manifestations can be easily eliminated. They can be removed by giving the patient a lot of liquid without gas, and then inducing vomiting. You need to do this to cleanse your stomach. In order for the drug to start working, you do not need to chew the tablets; they need to be swallowed whole with the required amount of water.

Interaction of Kagocel with other drugs

Does Kagocel help with colds? There is no doubt about its effectiveness, since it actively interacts with other medications aimed at eliminating the influence of viruses and infections. The product also enhances the effect of immunomodulators on the body. If such a need arises, it can be included in therapy together with antibiotics, since Kagocel enhances their positive effect.

The shelf life of the medicine is 4 years from the date of release and 1 year from the moment the package is opened. To store the drug, you need to choose a place protected from sunlight and rays, which will also be inaccessible to children. The optimal storage temperature, which will not affect the quality and effectiveness of the composition, is no higher than 25 degrees.

It is important to remember that there is no exact information about how the medication interacts with complex treatment programs. Despite the good indicators of medical research, there are no documents allowing the drug to reach the global level - not enough information has been received, not all the data that would be of interest to potential buyers of this drug is known. Thus, the drug is still a kind of experiment, but showing positive results at this stage of its existence.

Side effects of Kagocel and contraindications for use

Usually, all symptoms disappear immediately after discontinuation of the drug or completion of the course. Allergic skin reactions, atopic rhinitis, slight irritability, and mild muscle weakness may develop.

There are contraindications for Kagocel, which should be taken into account before starting therapy.

The list of contraindications for the use of this medicine includes:

  • individual intolerance to the main components;
  • pregnancy and lactation;
  • early childhood up to 3 years of age.

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Kagocel instructions

Instructions for use of the drug Kagocel will acquaint the consumer with all the necessary information on using it for treatment. The accompanying sheet gives a detailed description of the composition of the drug and its dosage form, and also informs about the terms and conditions of storage. In addition, indications for use and methods of its implementation, pharmacological action and use of Kagocel by various categories of patients are outlined. Warning information is given about the side effects of the drug, contraindications and overdose. The instructions also provide information about drug interactions between Kagocel and other medications and provide reviews from patients who have already used it for treatment.

Kagocel composition

The active substance of the drug is the substance Kagocel in the required concentration, which is supplemented with auxiliary components in the amount required to obtain a tablet weight of 100 milligrams. For this purpose, the substances taken were potato starch, calcium stearate and ludipress.

Kagocel release form

The drug is supplied to pharmacies in the form of round, biconvex tablets, which may have a creamy-brown color with inclusions. The container for the drug is cardboard packs, which contain a contoured blister pack with a dozen tablets.

Storage period and conditions

The drug can be stored in ordinary shaded, dry rooms where the air temperature does not exceed 25 degrees. Storage and use of the drug is provided for two years. Children should not have access to Kagocel storage areas.

Pharmacology

Kagocel is an antiviral drug and an inducer of interferon synthesis.

Taking the drug can cause the formation of a mixture of alpha and beta interferons in the body, which is called late interferon and has high activity against viruses.

Kagocel produces interferon in each of the body cell populations that take part in the antiviral response. The maximum value of interferon entering the blood serum with Kagocel can be achieved after two days. That’s why the drug has such a long-lasting effect, because when taken regularly, the dynamics of interferon accumulation increases and it circulates in the bloodstream for at least four or five days.

The therapeutic dose of the drug Kagocel is non-toxic and does not have the ability to accumulate in the body. The drug has no mutagenic or tetratogenic properties. It also has neither carcinogenic nor embryotoxic effects.

If Kagocel was prescribed before the fourth day after the acute infection occurred, the drug will still be able to effectively cope with it.

For prevention purposes, the drug is suitable at any time, especially after direct contact with a carrier of the infection has taken place.

How to take Kagocel for children and adults, dosage and recommendations

It is worth talking about how to take Kagocel for various conditions that require strengthening immune defense and antiviral action. The tablets should only be taken orally; the manufacturer does not recommend any other methods of use. Before taking the tablets, do not break them, remove them from the film coating, divide them into parts, or crush them.

Separately, we will talk about how to take Kagocel for children, since for this age group there are a number of practical restrictions. First of all, it is worth knowing that “Kagocel” can be given to children for preventive and therapeutic purposes after reaching the age of 3 years. There is no special dosage form available for this; the standard dosage of the drug is used, taking into account the difference in the number of tablets taken per day and per course of treatment.

"Kagocel" for adults is initially recommended for use in accordance with the therapeutic regimens proposed by the manufacturer. However, if there is no positive dynamics in the patient’s condition for 3 days, the dosage of Kagocel is selected individually, taking into account the parameters of the general condition of the body, body weight, age and other factors.

Dosage of Kagocel for adults and children

Treatment of acute respiratory viral infections, acute respiratory infections and influenza in adults

Begins no later than 4 days from the onset of the disease. The first 2 days - 2 tablets 3 times at equal intervals. 3rd and 4th day 1 tablet 3 times a day

Prevention of viral infections in adults

1st and 2nd days, 2 tablets once a day, then do not take the drug for 5 days

Treatment of viral infections in children aged 3 to 6 years

The first 2 days, 1 tablet 2 times a day, the next 2 days, 1 tablet 1 time a day

Treatment of viral infections in children aged 6 to 13 years

The first 2 days, 1 tablet 3 times a day, the next 2 days, 1 tablet 2 times a day

Preventive use of the drug in children from 3 to 12 years old

1st and 2nd days, 1 tablet 1 time per day, then do not take the drug for 5 days

Side effects

Allergic reactions may occur as side effects when taking the drug, the occurrence of which should be reported to your doctor immediately.

Overdose

In case of an overdose of Kagocel, the victim should be given assistance by prescribing plenty of fluids and then inducing vomiting.

Drug interactions

Simultaneous use of the drug Kagocel with other antiviral drugs, as well as immunomodulatory agents and antibiotics can summarize their therapeutic effect.

Additional instructions

In order for a positive therapeutic effect to be obtained from therapy with Kagocel, its use should be started no later than four days from the onset of the disease if the moment of its occurrence was missed for treatment.

The use of other antiviral drugs, as well as antibiotics and immunomodulatory agents in the treatment of Kagocel is encouraged.

Cold tablets Kagocel Instructions for use, How to take it for adults and children

No person is immune from colds. Adults, children, the elderly and athletes can encounter the problem, so you need to know which drugs can quickly have a positive effect, relieve symptoms and act on the source.

The drug Kagocel in the form of compact tablets for colds is an effective medicine used in the main course of therapeutic treatment, as well as for prophylactic use during the period of greatest risk of infection.

Group – antiviral and immunomodulatory agents.

Composition and properties of Kagocel

The constituent elements of Kagocel indicate its natural origin, the absence of components of chemical origin, and reduce the likelihood of an allergic reaction and side effects. The main component that starts to work is Kagocel. One tablet of this component contains 12 mg. The effectiveness of the work is complemented by substances such as:

calcium stearate (salt of calcium and stearic acid);
crospovidone (improves the process of substance release, accelerates chemical reactions);
a substance called povidone is an enterosorbent in its properties;
lactose monohydrate (a component that people intolerant to this substance should pay attention to).

Additionally, the composition includes a natural and completely safe product - starch obtained from potatoes. The drug is packaged in cardboard boxes and blisters. One contains 10 tablets and instructions on how to use the product to achieve maximum results.

The main active ingredient (kagocel) is a unique composition that is aimed at stimulating natural substances. As a result of the synthesis launched by it, the body resumes (strengthens) the production of its own antiviral proteins, as well as interferons. The work is intensive, but does not lead to negative processes.

The main component is a preparation of biological synthesis - a combination of cotton polymer and cellulose, resulting in a complex sodium salt. The therapeutic effect in this case is mild, the action is direct and indirect.

Since the effect is not intense, the medication can be used to treat colds and viral infections that occur in childhood.

The maximum possible positive effect from the use of cold medicine is observed if the therapeutic effect was started within the first 4 days from the onset of symptoms.

Such an impact is directly related to the rapid spread of viruses inside cells, since during this period they are most sensitive and vulnerable to the effects of interferons directed at them.

In accordance with the characteristics of interferon, Kagocel has the following medicinal properties:

  • elimination of microbes (any microorganisms cannot resist the effects of the medication for long);
  • antiviral (viruses stop developing, weaken and die without causing serious harm to the body if the product is started in a timely manner);
  • strengthening the natural strength of the immune system;
  • radioprotector.

About 20% of the active substance, after carrying out the necessary therapy to restore strength and function of the immune system, accumulates in the liver, but the drug is excreted through the gastrointestinal tract - up to 91% and the remainder (about 10%) with liquids. The accumulation of the main component and excipients in the body was not observed during medical studies.

Indications for use: features of the effect of the drug Kagocel

Preventive or therapeutic use of the drug Kagocel for colds shows good results - the recovery process proceeds faster, symptoms disappear 1-3 days after the start of treatment. In addition to the usual acute respiratory infections, the medication is included in the active recovery program for adults and children if they are diagnosed with:

  • diseases that have developed in the body due to the activity of viruses (ARVI);
  • influenza (including those accompanied by severe symptoms);
  • herpes (occurring in a simple form).

Is it possible to take Kagocel during pregnancy and with alcohol?

Many patients are interested in how Kagocel and alcohol combine with each other, because situations are not uncommon when the drug is taken for prophylactic purposes and various celebrations occur during this period. Also, some women think that Kagocel can be used during pregnancy to prevent and treat viral infections. And these two questions sometimes become cornerstone, so let’s look at them in more detail.

So, is it possible to take Kagocel during pregnancy and breastfeeding? Are such methods of therapy justified? The vast majority of doctors, based on the recommendations of researchers and drug manufacturers, recommend that expectant mothers, if possible, refrain from taking this drug. There is a risk of harmful effects on the tissues of the developing fetus and provoke immune disorders in the child, which in the future can lead to quite serious pathologies. This is due to the ability of the active substance to freely penetrate the placental barrier.

Clinical and laboratory studies have shown that the concentration of the drug in breast milk is also high enough to cause potential harm to the infant's developing immune system.

In this regard, such treatment methods should be excluded during pregnancy, and during breastfeeding, if it is necessary to take the drug, the baby should be weaned from the breast for a period from the start of therapy until 7 days after taking the last dose.

Taking Kagocel and alcohol at the same time is also strictly prohibited. Stimulated production of interferons under the influence of ethyl alcohol can cause severe forms of retinopathy (blindness), neuropathy (claudication), depressive syndrome with severe insomnia. In some cases, such changes are irreversible.

You can drink alcoholic beverages only 7 days after completing the full course of treatment.

Kagocel analogues

Like many medications, Kagocel has many substitutes on the pharmaceutical market that have a similar therapeutic effect. Strictly speaking, they cannot be considered analogues, since they have a different active composition from Kagocel, however, they take on this role due to the ability to provide a similar therapeutic effect.

Cheap analogs of Kagocel

For those patients who find Kagocel expensive, they can purchase cheaper analogues. Such drugs can also be found in any pharmacy. They are available without a doctor's prescription and will help with colds just as well. The antiviral drugs “Arbidol” and “Anaferon” have pharmacological properties similar to the drug Kagocel.

Arbidol or Kagocel

Among the many options for antiviral drugs, Arbidol is by far the most popular drug that replaces Kagocel. Both medications have similar therapeutic effects on the body in the fight against colds. Therefore, choosing between them can be quite difficult. Since both have a similar therapeutic effect and also have similar side effects, perhaps the patient can reserve the right to choose. However, many therapists are still inclined to believe that Kagocel can be recognized as a more proven drug in the field of treatment and prevention of influenza and ARVI.

Kagocel®

ATX

Pharmacological groups

  • Antiviral (except HIV) drugs
  • Interferon inducers

Nosological classification (ICD-10)

  • B00 Herpes simplex virus infections
  • J06 Acute upper respiratory tract infections of multiple and unspecified localization
  • J11 Influenza, virus not identified

Dosage form and composition

Description of the dosage form

The tablets are cream to brown, round, biconvex, interspersed.

Pharmacological action

Pharmacological action- immunomodulatory, antiviral.

Pharmacodynamics

The main mechanism of action of Kagocel ® is the ability to induce interferon production. Causes the formation in the human body of the so-called. late interferon, which is a mixture of alpha and beta interferons with high antiviral activity. Kagocel ® causes the production of interferon in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one dose of Kagocel ® is taken orally, the interferon titer in the blood serum reaches maximum values ​​after 48 hours. The body's interferon response to the administration of Kagocel ® is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of interferon accumulation in the intestine when Kagocel ® is taken orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, interferon production reaches high levels only 48 hours after taking Kagocel ® , while in the intestine the maximum interferon production is observed after 4 hours.

Kagocel ®, when prescribed in therapeutic doses, is non-toxic and does not accumulate in the body. The drug does not have mutagenic or teratogenic properties, is not carcinogenic and does not have an embryotoxic effect.

The greatest effectiveness in treatment with Kagocel ® is achieved when it is prescribed no later than the 4th day from the onset of acute infection. For preventive purposes, the drug can be used at any time, incl. and immediately after contact with an infectious agent.

Pharmacokinetics

24 hours after administration to the body, Kagocel ® accumulates mainly in the liver, and to a lesser extent in the lungs, thymus, spleen, kidneys, and lymph nodes. Low concentrations are observed in adipose tissue, heart, muscles, testes, brain, blood plasma. The low content of Kagocel ® in the brain is explained by the high molecular weight of the drug, which impedes its penetration through the BBB. In the blood plasma the drug is found predominantly in bound form.

With daily repeated administration of Kagocel ® V d of the drug varies widely. The accumulation of the drug is especially pronounced in the spleen and lymph nodes. When taken orally, about 20% of the administered dose of the drug enters the general bloodstream. The absorbed drug circulates in the blood, mainly in the form associated with macromolecules: 47% with lipids, 37% with proteins. The unbound portion of the drug is about 16%.

Removal: The drug is excreted from the body mainly through the intestines: 7 days after administration - 88% of the administered dose, incl. 90% - through the intestines and 10% - through the kidneys. The drug was not detected in exhaled air.

Indications of the drug Kagocel ®

Adults:

prevention and treatment of influenza and other acute respiratory viral infections (ARVI);

herpes treatment.

Children:

treatment of influenza and other acute respiratory viral infections in children over 3 years of age;

prevention of influenza and other acute respiratory viral infections in children aged 3 years and older.

Contraindications

increased individual sensitivity;

lactase deficiency;

lactose intolerance;

glucose-galactose malabsorption;

pregnancy;

age up to 3 years.

Side effects

Allergic reactions may develop.

Interaction

Combines well with other antiviral drugs, immunomodulators and antibiotics (additive effect).

Directions for use and doses

Inside.

For the treatment of influenza and ARVI in adults 2 tablets are prescribed. 3 times a day in the first 2 days, in the next 2 days - 1 tablet. 3 times a day. In total there are 18 tablets per course of treatment, course duration is 4 days.

Prevention of acute respiratory viral infections in adults carried out in 7-day cycles: 2 days, 2 tablets. Once a day, then a break for 5 days, and the cycle is repeated. The duration of the preventive course is from 1 week to several months.

For the treatment of herpes in adults 2 tablets are prescribed. 3 times a day for 5 days. A total of 30 tablets per course of treatment, course duration is 5 days.

For the treatment of influenza and ARVI in children aged 3 to 6 years 1 tablet is prescribed. 2 times a day in the first 2 days, in the next 2 days - 1 tablet. 1 time per day. In total there are 6 tables per course, course duration is 4 days.

Thank you

The site provides reference information for informational purposes only. Diagnosis and treatment of diseases must be carried out under the supervision of a specialist. All drugs have contraindications. Consultation with a specialist is required!

General information

According to recent statistics, the average adult suffers from a cold, flu or acute respiratory illness 2 to 3 weeks a year. About half of this time occurs in November-December. At this time of year, the maximum spread of influenza and ARVI is observed.

The pace of modern life in large cities requires a person to save time and effort. Undoubtedly, the above diseases have a very unfavorable effect on health and general well-being. However, despite the fact that colds and flu are considered relatively benign diseases, preventing or alleviating these diseases is not an easy task. Once in the body, the virus multiplies quickly, provoking a number of symptoms: rhinitis, cough, headache, loss of strength and loss of general tone, hyperthermia.

Today, people increasingly need effective and convenient drugs that will prevent, or minimize and alleviate the course of the disease.

Humanity still does not have drugs at its disposal that can cope with viral infection with 100% efficiency. Today, antiviral medications are imperfect, but their number and variety are growing, and their effectiveness is increasing every year.

Russian antiviral drug Kagocel- This is another domestic drug for colds, flu and acute respiratory diseases.

Most antiviral drugs sold in Russia have a positive effect only when treatment is started early (on days 1-2 of the disease). Kagocel, in turn, is effective at any stage of the disease. It not only alleviates and shortens the course of the disease, but also significantly reduces the likelihood of complications. In addition, the drug is safe and does not cause side effects (with the exception of rare cases of allergic reactions). Therefore, it is approved for use in children over 3 years of age.

Kagocel was developed by the Nearmedic Plus company (RF), created on the basis of the Research Institute of Epidemiology and Microbiology named after. N.F. Gamaleya RAMS. The drug was approved by the Russian Ministry of Health and Social Development as a medicine recommended for the prevention and treatment of acute respiratory viral infections, influenza, as well as for the treatment of pathologies associated with herpes virus infection. In addition, the drug was included in the list of vital and essential medicines, due to which it was included in the state system. procurement Produced since 2005. Available in pharmacies without a prescription.

Interferon inducers

Since the production of interferon is one of the first immune responses to viral infection, stimulators of the production of this protein occupy a special place among antiviral drugs.

Interferon inducers do not cause an immune response and are not capable of causing an overdose. Once in the body, drugs of this group stimulate the production of interferons in optimal quantities.

Interferon inducers are divided into two groups: artificial and natural. The drug Kagocel, in turn, belongs to the second group. It stimulates the production of alpha, beta, and gamma interferons in the human body, which have a high antiviral effect.

Mechanism of action of the drug

Since during the preparation of the drug the active substance is bound to the cellulose base, Kagocel is practically not absorbed in the digestive tract (no more than 20% of the active substance is absorbed).

Kagocel enhances the activity of interferons (specific cellular proteins that protect the body from viruses) in the body.

By acting on the body, Kagocel induces the production of interferons in the body, which have a pronounced antiviral effect. The effect of the drug lasts 5-7 days. Due to the long-lasting effect of the drug, it is convenient to use it for the prevention of acute respiratory diseases and influenza in small doses, short courses and at any time of contact with the spreader of the disease.

Kagocel enhances the production of interferon in all cells that are part of the antiviral immune system: in B-cells, macrophagocytes, granular leukocytes, fibroblasts, endothelial cells.

However, the effect of Kagocel is not limited to the induction of interferon production. The drug also stimulates the release of cytokines, activates cellular immunity and natural killer cells.

The effect of the drug on the body lasts on average 5 days, during which the produced interferon circulates in the circulatory system. At the same time, the active substance accumulates in the intestines 4 hours after administration. After a single use of the drug in a standard dose, the concentration of interferon in the blood increases significantly, reaching a maximum after two days. The maximum concentration of interferon in the blood persists for 2-3 days.

According to the results of numerous clinical trials, with repeated daily use of the drug, the active substance enters various organs and tissues in uneven proportions. A day after entering the body, most of the active substance is concentrated in the liver. Also, in small concentrations, the drug accumulates in the lungs, spleen, kidneys, thymus gland and lymph nodes. The drug accumulates least in muscle tissue, heart, adipose tissue, brain and blood. When taken orally, approximately 20% of the active substance enters the bloodstream. In the blood, 47% of kagocel is bound to blood lipids, 37% to proteins, 16% circulates in free form. The molecules of kagocel are quite massive, so it does not penetrate the blood-brain barrier, which prevents it from entering the brain. The drug is eliminated mainly through the digestive tract. 6-7 days after completion of the course of treatment, approximately 88% of the active substance is removed from the body. In this case, 90% is excreted through the gastrointestinal tract, and 10% through the kidneys. Excretion of the drug through the lungs has not been established.

Indications

  • For adults, Kagocel is indicated for the treatment of viral infectious diseases, as well as the prevention of colds, flu and other acute respiratory infections, for the treatment of diseases associated with herpes virus infection;
  • for children over 6 years of age, the drug is indicated for the prevention and treatment of influenza, colds and other acute respiratory diseases;
  • Children 3-6 years old are indicated for the treatment of influenza, colds and other acute respiratory infections.

Contraindications

  • hypersensitivity to the components of the drug;
  • age up to 3 years;
  • pregnancy period;
  • intolerance to glucose and galactose.

Directions for use and doses

Kagocel is administered orally.

For adults
For flu, colds and other acute respiratory infections, take two tablets. 3 times a day for the first 2 days, then one tablet 3 times a day. Duration of the course – 4 days.
To prevent influenza, colds and other acute respiratory infections, 2 tablets are prescribed. 1 time per day for 7 days. Then a 5-day break is taken, after which, if necessary, the 7-day cycle is repeated. The duration of the preventive course is determined by the attending physician and ranges from 7 days to 3-5 months.
To treat herpes virus infection, take 2 tablets. 3 times a day. The duration of the course is 5 days.

Children 3-6 years old
For flu, colds and other acute respiratory infections, take 1 tablet. 2 times a day for two days, then 1 tablet. per day. The duration of the course is 4 days.

Children over 6 years old
For flu, colds and other acute respiratory infections, take 1 tablet. 3 times a day for two days, then 1 tablet. 2 times a day.
To prevent influenza, colds and other acute respiratory infections, 2 tablets are prescribed. 1 time per day for a week. Then a 5-day break is taken, after which the 7-day cycle is repeated. The duration of prophylaxis depends on various factors and is determined by the attending physician. Prevention lasts from 7 days to 3-5 months.

Overdose

In case of an overdose of Kagocel, drinking plenty of fluids followed by inducing vomiting is indicated. It is strongly recommended that you seek medical advice before resuming treatment.

Side effects

Rarely - an allergy to the components of the medication.

Interaction with other drugs

The drug Kagocel combines well with immunostimulants, antibiotics (complements their effect), and other antiviral medications.

Special instructions

The maximum therapeutic effect of the drug is achieved if treatment is started within a period not exceeding 3 days from the onset of the acute phase of the disease. To prevent influenza, colds and other acute respiratory diseases, the drug is used at any time, or after contact with the spreader of the disease.

Storage conditions

Store out of the reach of children, at a temperature below 25 degrees.

Bird flu

One of the most promising methods for preventing avian influenza is vaccination and the use of interferon inducers.

Many scientists note that the above method deserves wider use in therapeutic and clinical practice, incl. in the prevention of influenza and acute respiratory diseases. At the moment, there is not a single vaccine against avian influenza, the effectiveness of which has been confirmed in practice. Kagocel, by inducing the production of interferon in the body, enhances protection and helps protect against all strains of viruses. Therefore, in the event of a bird flu epidemic, this drug can serve as an effective means of preventing this dangerous pathology.

Prevention of influenza through vaccination provides protection only against the influenza virus, while the risk of acute respiratory viral infection is not reduced. Epidemics of influenza and ARVI often occur simultaneously. Meanwhile, influenza vaccination goes well with the use of interferon inducers, incl. Kagotsela. Therefore, the integrated use of the above methods provides more reliable protection against viral infection.

Kagocel for children

Today, this drug is widely used in the treatment and prevention of seasonal viral diseases in adults. But it is indicated for children as a therapeutic drug only from the age of 6, since to date no clinical trials have been conducted on children and pregnant women. In order to prevent influenza and ARVI, the medication is approved for children over 3 years of age.

The drug affects the child’s body in the same way as it does the adult’s body, because interferon begins to be produced in the body from the moment of birth. And Kagocel, in turn, simply stimulates the release of this protein in large quantities.

Interferon can provide great support to children during the ARVI epidemic season. Therefore, interferon inducers such as Kagocel should not be neglected - it will alleviate the course of the disease and reduce the risk of complications without causing any side effects.

Assessing the effectiveness of herpes treatment

This study was conducted by the Central Research Laboratory of the Omsk State Medical Academy

The herpes virus is one of the most common microorganisms that infect the human body. According to official statistics, approximately 90% of people living in cities are carriers of herpes viruses of various forms.

The purpose of the study was to evaluate the drug Kagocel in the treatment of herpes infection.

146 people took part in the study, among them 63 were men, 83 were women. The diagnosis of genital herpes was made in 115 patients, oral herpes in 31. Kagocel was used in the treatment in the form of tablets for oral administration (the active substance in 1 tablet is 0.012 g).

The subjects were divided into three groups: the first group was prescribed Kagocel exclusively, the second - Kagocel in combination with