Contraindications for Kagocel. Medicinal reference book geotar. How to take the medicine correctly

Kagocel is an immunostimulating, antiviral drug. Instructions for use recommend taking 12 mg tablets for the treatment of herpes in adult patients. Reviews from patients and doctors confirm that this drug helps in the treatment and prevention of influenza and other acute respiratory viral infections in children (in particular, over the age of 3 years) and adults.

Release form and composition

Kagocel is produced in the form of tablets: round, biconvex, brown to cream in color with inclusions (10 pieces in strip packs, 1 pack in a cardboard box).

1 tablet contains: active substance - Kagocel - 12 mg.

Pharmacological properties

Kagocel is an antiviral drug. The instructions for use indicate that this inducer of interferon synthesis causes the formation in the body of so-called late interferon, which is a mixture of alpha and beta interferons with high antiviral activity.

The drug causes the production of interferon in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells.

When one dose of Kagocel is taken orally, the interferon titer in the blood serum reaches maximum values ​​after 48 hours. The body's interferon response to the administration of the drug is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream.

The dynamics of interferon accumulation in the intestine when taking the drug orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, the interferon content reaches high values ​​only 48 hours after taking the drug Kagocel, while in the intestine the maximum interferon production is observed after 4 hours.

The greatest effectiveness of treatment is achieved when it is prescribed no later than the 4th day from the onset of acute infection. For preventive purposes, the drug can be used at any time, incl. and immediately after contact with an infectious agent.

What does Kagocel help with?

Indications for use of the drug include:

  • herpes (treatment in adults);
  • influenza and other acute respiratory viral infections (treatment and prevention in adults and children over 3 years of age).

Instructions for use

Kagocel is taken orally. For adults, the drug is prescribed depending on the indications:

Treatment of acute respiratory viral infections (ARVI) and influenza: in the first 2 days of use - 3 times a day, 24 mg (2 tablets), in the next 2 days the single dose is reduced by 2 times (a total of 18 tablets per course).

Prevention of acute respiratory viral infections and influenza: 2 days of use - 24 mg once a day, then a break for 5 days. Cycles of 7 days can be repeated (the duration of the preventive course varies from 7 days to several months).

Treatment of herpes: 3 times a day, 24 mg for 5 days (a total of 30 tablets per course).

For the treatment of ARVI and influenza, children are prescribed:

  • 3-6 years: in the first 2 days of use - 2 times a day, 12 mg (1 tablet), in the next 2 days - 1 time a day, 12 mg (total 6 tablets per course).
  • From 6 years: in the first 2 days of use - 3 times a day, 12 mg, in the next 2 days - 2 times a day, 12 mg (a total of 10 tablets per course).
  • For the prevention of ARVI and influenza, the drug should be taken in courses of 7 days for children: 2 days – 12 mg once a day, then a break for 5 days. Cycles of 7 days can be repeated (the duration of the preventive course varies from 7 days to several months).

Contraindications

  • increased individual sensitivity;
  • children under 3 years of age;
  • pregnancy;
  • lactase deficiency, lactose intolerance, glucose-galactose malabsorption;
  • lactation period (breastfeeding).

Side effects

allergic reactions.

Children, pregnancy and breastfeeding

The drug is contraindicated for use during pregnancy and lactation (breastfeeding). Kagocel, when prescribed in therapeutic doses, is non-toxic and does not accumulate in the body. The drug does not have mutagenic or teratogenic properties, is not carcinogenic and does not have embryotoxic effects.

The drug Kagocel is contraindicated in children under 3 years of age. For the treatment of influenza and ARVI, children aged 3 to 6 years are prescribed 1 tablet 2 times a day in the first 2 days, 1 tablet 1 time a day in the next 2 days. A total of 6 tablets per course lasting 4 days.

For the treatment of influenza and ARVI, children aged 6 years and older are prescribed 1 tablet 3 times a day in the first 2 days, 1 tablet 2 times a day in the next 2 days. A total of 10 tablets for a course lasting 4 days.

In children aged 3 years and older, prevention of influenza and ARVI is carried out in 7-day cycles: 2 days - 1 tablet once a day, a break for 5 days, then the cycle is repeated. The duration of the preventive course is from 1 week to several months.

special instructions

To achieve a therapeutic effect, it is recommended to start taking Kagocel no later than the fourth day from the onset of the disease. The medicine combines well with antibiotics, immunomodulators and other antiviral drugs.

Drug interactions

With the simultaneous use of the drug Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect is observed (they enhance the effect of each other).

Analogues of the drug Kagocel

The medicine has no complete analogues for the active substance.

Antiviral agents include:


Vacation conditions and price

The average price of Kagocel in Moscow is 235 rubles. In Kyiv you can buy medicine for 291 hryvnia, in Kazakhstan - for 1590 tenge. In Minsk, pharmacies offer 12 mg tablets for 6-7 bel. rubles Dispensed from pharmacies with a prescription.

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Side effects of Kagocel and contraindications for use

Usually, all symptoms disappear immediately after discontinuation of the drug or completion of the course of treatment. Allergic skin reactions, atopic rhinitis, slight irritability, and mild muscle weakness may develop.

There are contraindications for Kagocel, which should be taken into account before starting therapy.

The list of contraindications for the use of this drug includes:

  • individual intolerance to the main components;
  • pregnancy and lactation;
  • early childhood up to 3 years of age.

If you have questions for your doctor, please ask them on the consultation page. To do this, click on the button:

Kagocel instructions

Instructions for use of the drug Kagocel will acquaint the consumer with all the necessary information on using it for treatment. The accompanying sheet gives a detailed description of the composition of the drug and its dosage form, and also informs about the terms and conditions of storage. In addition, indications for use and methods of its implementation, pharmacological action and use of Kagocel by various categories of patients are outlined. Warning information is given about the side effects of the drug, contraindications and overdose. The instructions also provide information about drug interactions between Kagocel and other medications and provide reviews from patients who have already used it for treatment.

Kagocel composition

The active substance of the drug is the substance Kagocel in the required concentration, which is supplemented with auxiliary components in the amount required to obtain a tablet weight of 100 milligrams. For this purpose, the substances taken were potato starch, calcium stearate and ludipress.

Kagocel release form

The drug is supplied to pharmacies in the form of round, biconvex tablets, which may have a creamy-brown color with the presence of inclusions. The container for the drug is cardboard packs, which contain a contoured blister pack with a dozen tablets.

Storage period and conditions

The drug can be stored in ordinary shaded, dry rooms where the air temperature does not exceed 25 degrees. Storage and use of the drug is provided for two years. Children should not have access to Kagocel storage areas.

Pharmacology

Kagocel is an antiviral drug and an inducer of interferon synthesis.

Taking the drug can cause the formation of a mixture of alpha and beta interferons in the body, which is called late interferon and has high activity against viruses.

Kagocel produces interferon in each of the body cell populations that take part in the antiviral response. The maximum value of interferon entering the blood serum with Kagocel can be achieved after two days. That’s why the drug has such a long-lasting effect, because when taken regularly, the dynamics of interferon accumulation increases and it circulates in the bloodstream for at least four or five days.

The therapeutic dose of the drug Kagocel is non-toxic and does not have the ability to accumulate in the body. The drug has no mutagenic or tetratogenic properties. It also has neither carcinogenic nor embryotoxic effects.

If Kagocel was prescribed before the fourth day after the acute infection occurred, the drug will still be able to effectively cope with it.

For preventive purposes, the drug is suitable at any time, especially after direct contact with a carrier of the infection has taken place.

How to take Kagocel for children and adults, dosage and recommendations

It is worth talking about how to take Kagocel for various conditions that require strengthening immune defense and antiviral action. The tablets should only be taken orally; the manufacturer does not recommend any other methods of use. Before taking the tablets, do not break them, remove them from the film coating, divide them into parts, or crush them.

Separately, we will talk about how to take Kagocel for children, since for this age group there are a number of practical restrictions. First of all, it is worth knowing that “Kagocel” can be given to children for preventive and therapeutic purposes after reaching the age of 3 years. There is no special dosage form available for this; the standard dosage of the drug is used, taking into account the difference in the number of tablets taken per day and per course of treatment.

"Kagocel" for adults is initially recommended for use in accordance with the therapeutic regimens proposed by the manufacturer. However, if there is no positive dynamics in the patient’s condition for 3 days, the dosage of Kagocel is selected individually, taking into account the parameters of the general condition of the body, body weight, age and other factors.

Dosage of Kagocel for adults and children

Treatment of acute respiratory viral infections, acute respiratory infections and influenza in adults

Begins no later than 4 days from the onset of the disease. The first 2 days - 2 tablets 3 times at equal intervals. 3rd and 4th day 1 tablet 3 times a day

Prevention of viral infections in adults

1st and 2nd days, 2 tablets 1 time per day, then do not take the drug for 5 days

Treatment of viral infections in children aged 3 to 6 years

The first 2 days, 1 tablet 2 times a day, the next 2 days, 1 tablet 1 time a day

Treatment of viral infections in children aged 6 to 13 years

The first 2 days, 1 tablet 3 times a day, the next 2 days, 1 tablet 2 times a day

Preventive use of the drug in children from 3 to 12 years old

1st and 2nd days, 1 tablet 1 time per day, then do not take the drug for 5 days

Side effects

Allergic reactions may occur as side effects when taking the drug, the occurrence of which should be reported to your doctor immediately.

Overdose

In case of an overdose of Kagocel, the victim should be given assistance by prescribing plenty of fluids and then inducing vomiting.

Drug interactions

Simultaneous use of the drug Kagocel with other antiviral drugs, as well as immunomodulatory agents and antibiotics can summarize their therapeutic effect.

Additional instructions

In order for a positive therapeutic effect to be obtained from therapy with Kagocel, its use should be started no later than four days from the onset of the disease if the moment of its occurrence was missed for treatment.

The use of other antiviral drugs, as well as antibiotics and immunomodulatory agents in the treatment of Kagocel is encouraged.

Cold tablets Kagocel Instructions for use, How to take it for adults and children

No person is immune from colds. Adults, children, the elderly and athletes can encounter the problem, so you need to know which drugs can quickly have a positive effect, relieve symptoms and act on the source.

The drug Kagocel in the form of compact tablets for colds is an effective medicine used in the main course of therapeutic treatment, as well as for prophylactic use during the period of greatest risk of infection.

Group – antiviral and immunomodulatory agents.

Composition and properties of Kagocel

The constituent elements of Kagocel indicate its natural origin, the absence of components of chemical origin, and reduce the likelihood of an allergic reaction and side effects. The main component that starts to work is Kagocel. One tablet of this component contains 12 mg. The effectiveness of the work is complemented by substances such as:

calcium stearate (salt of calcium and stearic acid);
crospovidone (improves the process of substance release, accelerates chemical reactions);
a substance called povidone is an enterosorbent in its properties;
lactose monohydrate (a component that people intolerant to this substance should pay attention to).

Additionally, the composition includes a natural and completely safe product - starch obtained from potatoes. The drug is packaged in cardboard boxes and blisters. One contains 10 tablets and instructions on how to use the product to achieve maximum results.

The main active ingredient (kagocel) is a unique composition that is aimed at stimulating natural substances. As a result of the synthesis launched by it, the body resumes (strengthens) the production of its own antiviral proteins, as well as interferons. The work is intensive, but does not lead to negative processes.

The main component is a preparation of biological synthesis - a combination of cotton polymer and cellulose, resulting in a complex sodium salt. The therapeutic effect in this case is mild, the action is direct and indirect.

Since the effect is not intense, the medication can be used to treat colds and viral infections that occur in childhood.

The maximum possible positive effect from the use of cold medicine is observed if the therapeutic effect was started within the first 4 days from the onset of symptoms.

Such an impact is directly related to the rapid spread of viruses inside cells, since during this period they are most sensitive and vulnerable to the effects of interferons directed at them.

In accordance with the characteristics of interferon, Kagocel has the following medicinal properties:

  • elimination of microbes (any microorganisms cannot resist the effects of the medication for long);
  • antiviral (viruses stop developing, weaken and die without causing serious harm to the body if the product is started in a timely manner);
  • strengthening the natural strength of the immune system;
  • radioprotector.

About 20% of the active substance, after carrying out the necessary therapy to restore strength and function of the immune system, accumulates in the liver, but the drug is excreted through the gastrointestinal tract - up to 91% and the remainder (about 10%) with liquids. The accumulation of the main component and excipients in the body was not observed during medical studies.

Indications for use: features of the effect of the drug Kagocel

Preventive or therapeutic use of the drug Kagocel for colds shows good results - the recovery process proceeds faster, symptoms disappear 1-3 days after the start of treatment. In addition to the usual acute respiratory infections, the medication is included in the active recovery program for adults and children if they are diagnosed with:

  • diseases that have developed in the body due to the activity of viruses (ARVI);
  • influenza (including those accompanied by severe symptoms);
  • herpes (occurring in a simple form).

Is it possible to take Kagocel during pregnancy and with alcohol?

Many patients are interested in how Kagocel and alcohol combine with each other, because situations are not uncommon when the drug is taken for prophylactic purposes and various celebrations occur during this period. Also, some women think that Kagocel can be used during pregnancy to prevent and treat viral infections. And these two questions sometimes become cornerstone, so let’s look at them in more detail.

So, is it possible to take Kagocel during pregnancy and breastfeeding? Are such methods of therapy justified? The vast majority of doctors, based on the recommendations of researchers and drug manufacturers, recommend that expectant mothers, if possible, refrain from taking this drug. There is a risk of harmful effects on the tissues of the developing fetus and provoke immune disorders in the child, which in the future can lead to quite serious pathologies. This is due to the ability of the active substance to freely penetrate the placental barrier.

Clinical and laboratory studies have shown that the concentration of the drug in breast milk is also high enough to cause potential harm to the infant's developing immune system.

In this regard, such treatment methods should be excluded during pregnancy, and during breastfeeding, if it is necessary to take the drug, the baby should be weaned from the breast for a period from the start of therapy until 7 days after taking the last dose.

Taking Kagocel and alcohol at the same time is also strictly prohibited. Stimulated production of interferons under the influence of ethyl alcohol can cause severe forms of retinopathy (blindness), neuropathy (claudication), depressive syndrome with severe insomnia. In some cases, such changes are irreversible.

You can drink alcoholic beverages only 7 days after completing the full course of treatment.

Kagocel analogues

Like many medications, Kagocel has many substitutes on the pharmaceutical market that have a similar therapeutic effect. Strictly speaking, they cannot be considered analogues, since they have a different active composition from Kagocel, however, they take on this role due to the ability to provide a similar therapeutic effect.

Cheap analogs of Kagocel

For those patients who find Kagocel expensive, they can purchase cheaper analogues. Such drugs can also be found in any pharmacy. They are available without a doctor's prescription and will help with colds just as well. The antiviral drugs “Arbidol” and “Anaferon” have pharmacological properties similar to the drug Kagocel.

Arbidol or Kagocel

Among the many options for antiviral drugs, Arbidol is by far the most popular drug that replaces Kagocel. Both medications have similar therapeutic effects on the body in the fight against colds. Therefore, choosing between them can be quite difficult. Since both have a similar therapeutic effect and also have similar side effects, perhaps the patient can reserve the right to choose. However, many therapists are still inclined to believe that Kagocel can be recognized as a more proven drug in the field of treatment and prevention of influenza and ARVI.

Kagocel is an antiviral drug that is effective against colds (ARVI, influenza, parainfluenza, rotavirus, herpes infection and others). The drug has antiviral, immunostimulating and radioprotective effects.

The active ingredient of the drug has a similar name: Kagocel. 1 tablet contains Kagocel 12 mg. Kagocel is a substance of the polyphenol group, obtained by synthesis from water-soluble carmoxymethylcellulose and cotton seed polyphenol.

The therapeutic effect of the pharmacological agent is provided by the active component, based on the ability of Kagocel to stimulate the formation of different types of interferon - the body's natural protective proteins, since specific protein structures activate enzymatic systems to suppress harmful microflora and viral colonies.

Since the production of interferon is one of the first immune responses to viral infection, stimulators of the production of this protein occupy a special place among antiviral drugs.

The drug helps increase the production of interferon in various cells involved in the formation of the immune response, including macrophages, granulocytes, T- and B-lymphocytes, endothelial cells and fibroblasts.

When using the drug in children and adult patients, regardless of the characteristics of the course of ARVI, the duration of its symptoms is reduced. It is also noted that the drug increases interferon levels in children and adults with initially insufficient levels.

Indications for use Kagocel

Thus, the indications for use of Kagocel imply its use in adults to prevent infection and treat pathologies of a viral nature. Most often, the medication is used for influenza infections and other respiratory pathologies of viral origin.

Indications for the use of Kagocel are:

  • herpes therapy in adult patients;
  • treatment and prevention of influenza and other acute respiratory viral infections in children (in particular, over the age of 3 years) and adults;
  • decreased immunity;
  • bacterial lesions (in complex therapy).

Kagocel can be prescribed together with antibiotics, antipyretics and antihistamines without fear of harm to health. But it is still better to do this no later than 3-4 days after the onset of severe symptoms of a cold.

Instructions for use Kagocel, dosage

Kagocel is intended for oral administration.

For the treatment of influenza and ARVI, adults are prescribed 2 tablets in the first 2 days. 3 times a day, in the next 2 days - 1 tablet. 3 times/day. A total of 18 tablets per course lasting 4 days.

If you need to cope with the herpes virus in the acute phase, you will have to take 30 Kagocel tablets in five days. Usually, such powerful immune support is enough to get rid of unpleasant rashes.

Kagocel for children

Children 3-6 years old with flu, colds and other acute respiratory infections take 1 tablet of Kagocel 2 times a day for two days, then 1 tablet. per day. The duration of the course is 4 days.

For the treatment of influenza and other respiratory viral infections in children over 6 years of age, 1 tablet of Kagocel 3 times a day is prescribed in the first 2 days, and 1 tablet 2 times a day in the next 2 days.

The total duration of treatment is 4 days.

Features of application

The drug does not affect the reaction rate when driving vehicles or working with complex mechanisms.

Kagocel tablets have maximum effectiveness against the proliferation of viruses if used no later than the fourth day after the onset of symptoms.

During treatment, it is undesirable to consume alcohol in any form.

Side effects and contraindications Kagocel

In general, Kagocel is well tolerated, provided that the dosage and recommendations for frequency of use are followed. In some cases, intolerance to the active substance Kagocel and the auxiliary components of the drug may occur.

The official annotation for the medication emphasizes that if any symptoms of intolerance appear, you should consult a doctor.

Overdose

If Kagocel is used incorrectly and overdose, there is a risk of developing allergies, headaches, abdominal cramps and gas formation.

Contraindications

One of the contraindications to the use of Kagocel is considered to be a person’s hypersensitivity to the main active ingredient or auxiliary components. At the same time, according to statistical data, few cases of individual intolerance to Kagocel have been registered.

Also, the medication is not used in the following situations:

  • Pregnancy and lactation;
  • Age up to 3 years;
  • Lactase deficiency, lactose intolerance, glucose-galactose malabsorption.

Analogues of Kagocel, list of drugs

Analogues of the drug Kagocel are (list):

  1. Altabor;
  2. Amizon;
  3. Amizonchik;
  4. Arbidol;
  5. Armenicum;
  6. Arpeflu;
  7. Groprinosin;
  8. Isoprinosine;
  9. Imusstat;
  10. Novirin;
  11. Panavir;
  12. Flavoside;
  13. Örebra;
  14. Cycloferon;
  15. Lycopid;
  16. Anaferon and others.

Important - instructions for use of Kagocel, price and reviews do not apply to analogues and cannot be used as a guide to the use of drugs of similar composition or action. All therapeutic prescriptions must be made by a doctor. When replacing Kagocel with an analogue, it is important to consult a specialist; you may need to change the course of therapy, dosages, etc. Do not self-medicate!

Pharmacodynamics

The main mechanism of action of Kagocel® is the ability to induce interferon production. Kagocel® causes the formation in the human body of so-called late interferon, which is a mixture of a- and b-interferons with high antiviral activity. Kagocel® causes interferon production in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one dose of Kagocel® is taken orally, the interferon titer in the blood serum reaches its maximum values ​​after 48 hours. The body's interferon response to Kagocel® administration is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of interferon accumulation in the intestine when Kagocel® is taken orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, interferon production reaches high values ​​only 48 hours after taking Kagocel®, while in the intestine the maximum interferon production is observed after 4 hours.

Kagocel®, when prescribed in therapeutic doses, is non-toxic and does not accumulate in the body. The drug does not have mutagenic or teratogenic properties, is not carcinogenic and does not have embryotoxic effects.

The greatest effectiveness in treatment with Kagocel® is achieved when it is prescribed no later than the 4th day from the onset of acute infection. For preventive purposes, the drug can be used at any time, including immediately after contact with the infectious agent.

Pharmacokinetics

24 hours after administration to the body, Kagocel® accumulates mainly in the liver, and to a lesser extent in the lungs, thymus, spleen, kidneys, and lymph nodes. Low concentrations are observed in adipose tissue, heart, muscles, testes, brain, blood plasma. The low content of Kagocel® in the brain is explained by the high molecular weight of the drug, which makes it difficult to penetrate the blood-brain barrier. In the blood plasma the drug is found predominantly in bound form.

With daily repeated administration of Kagocel®, the volume of distribution varies widely in all organs studied. The accumulation of the drug is especially pronounced in the spleen and lymph nodes. When taken orally, about 20% of the administered dose of the drug enters the general bloodstream. The absorbed drug circulates in the blood, mainly in the form associated with macromolecules: with lipids - 47%, with proteins - 37%. The unbound portion of the drug is about 16%.

Excretion: the drug is excreted from the body mainly through the intestines: 7 days after administration, 88% of the administered dose is excreted from the body, including 90% through the intestines and 10% through the kidneys. The drug was not detected in exhaled air.

Kagocel®

International nonproprietary name

Dosage form

Tablets, 12 mg

Compound

1 tablet contains:

active substance: kagocel® (in terms of dry matter) 12.00 mg.

Excipients: potato starch, calcium stearate, Ludipress (composition: lactose monohydrate, povidone (Kollidon 30), crospovidone (Kollidon CL)) to obtain a tablet weighing 100 mg.

Description

The tablets are cream to brown, round, biconvex with inclusions.

Pharmacotherapeutic group

Direct acting antiviral drugs. Other antiviral drugs.

ATX code: J05AX.

Pharmacological properties

Pharmacodynamics

The main mechanism of action of Kagocel® is the ability to induce interferon production. Kagocel® causes the formation in the human body of the so-called late interferon, which is a mixture of α- and β-interferons with high antiviral activity. Kagocel® causes interferon production in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one dose of Kagocel® is taken orally, the interferon titer in the blood serum reaches its maximum values ​​after 48 hours. The body's interferon response to Kagocel® administration is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of interferon accumulation in the intestine when Kagocel® is taken orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, interferon production reaches high values ​​only 48 hours after taking Kagocel®, while in the intestine the maximum interferon production is observed after 4 hours.

Kagocel®, when prescribed in therapeutic doses, is non-toxic and does not accumulate in the body. The drug does not have mutagenic or teratogenic properties, is not carcinogenic and does not have embryotoxic effects.

The greatest effectiveness in treatment with Kagocel® is achieved when it is prescribed no later than the 4th day from the onset of acute infection. For preventive purposes, the drug can be used at any time, including immediately after contact with the infectious agent.

Pharmacokinetics

24 hours after administration to the body, Kagocel® accumulates mainly in the liver, and to a lesser extent in the lungs, thymus, spleen, kidneys, and lymph nodes. Low concentrations are observed in adipose tissue, heart, muscles, testes, brain, blood plasma. The low content of Kagocel® in the brain is explained by the high molecular weight of the drug, which makes it difficult to penetrate the blood-brain barrier. In the blood plasma the drug is found predominantly in bound form.

With daily repeated administration of Kagocel®, the volume of distribution varies widely in all organs studied. The accumulation of the drug is especially pronounced in the spleen and lymph nodes. When taken orally, about 20% of the administered dose of the drug enters the general bloodstream. The absorbed drug circulates in the blood, mainly in the form associated with macromolecules: with lipids - 47%, with proteins - 37%. The unbound portion of the drug is about 16%.

Excretion: the drug is excreted from the body mainly through the intestines: 7 days after administration, 88% of the administered dose is excreted from the body, including 90% through the intestines and 10% through the kidneys. The drug was not detected in exhaled air.

Indications for use

Kagocel® is used in adults and children over the age of 3 years as a preventive and therapeutic agent for influenza and other acute respiratory viral infections (ARVI), as well as a therapeutic agent for herpes in adults.

Directions for use and doses

For oral administration.

For the treatment of influenza and ARVI, adults are prescribed 2 tablets 3 times a day in the first two days, 1 tablet 3 times a day in the next two days. A total of 18 tablets per course, course duration - 4 days.

Prevention of influenza and ARVI in adults is carried out in 7-day cycles: two days - 2 tablets once a day, 5 days break, then repeat the cycle. The duration of the preventive course is from one week to several months.

For the treatment of herpes in adults, 2 tablets are prescribed 3 times a day for 5 days. A total of 30 tablets per course, course duration - 5 days.

For the treatment of influenza and ARVI, children aged 3 to 6 years are prescribed 1 tablet 2 times a day in the first two days, 1 tablet 1 time a day in the next two days. A total of 6 tablets per course, course duration - 4 days.

For the treatment of influenza and ARVI, children over 6 years of age are prescribed 1 tablet 3 times a day in the first two days, 1 tablet 2 times a day in the next two days. A total of 10 tablets per course, course duration - 4 days.

Prevention of influenza and ARVI in children aged 3 years and older is carried out in 7-day cycles: two days - 1 tablet once a day, 5 days break, then repeat the cycle. The duration of the preventive course is from one week to several months.

Side effects

Allergic reactions may develop.

If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Contraindications

Pregnancy

Lactation period

Children under 3 years old

Hypersensitivity to the components of the drug

Lactase deficiency, lactose intolerance, glucose-galactose malabsorption

Drug interactions

Kagocel® combines well with other antiviral drugs, immunomodulators and antibiotics (additive effect).

special instructions

To achieve a therapeutic effect, Kagocel® should be taken no later than the fourth day from the onset of the disease.

Possibility and features of use by pregnant women and women during breastfeeding

Due to the lack of necessary clinical data, Kagocel® is not recommended for use during pregnancy and lactation.

Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms

The effect of the drug on the ability to drive vehicles and operate machinery has not been studied.